Dr
David LawrenceProfile page
Clinical Research Physician
Clinical Research
Orcid identifier0000-0002-5439-4039
- Clinical Research PhysicianClinical Research
BIO
My work spans multiple disciplines (clinical trials, epidemiology, diagnostics, health economics, anthropology) but is unified by an unwavering drive to reduce mortality and morbidity from advanced HIV disease.
I joined the Faculty of Infectious and Tropical Diseases in 2017 and was based in Gaborone, Botswana for four years where I worked as the Lead Clinician for the AMBIsome Therapy Induction OptimisatioN (AMBITION) trial. AMBITION was a phase III randomised controlled trial of a single, high-dose liposomal amphotericin regimen for HIV-associated cryptococcal meningitis and recruited patients from six sites across five countries in Southern Africa.
I returned to the UK in 2021 and following the success of the trial I am co-investigator on a number of research and non-research grants aimed at maximising the impact of the AMBITION regimen in routine care settings and applying research advances in cryptococcal meningitis to other HIV-associated fungal infections.
Alongside research I work two-days a week for the NHS as a HIV and Sexual Health doctor.
I joined the Faculty of Infectious and Tropical Diseases in 2017 and was based in Gaborone, Botswana for four years where I worked as the Lead Clinician for the AMBIsome Therapy Induction OptimisatioN (AMBITION) trial. AMBITION was a phase III randomised controlled trial of a single, high-dose liposomal amphotericin regimen for HIV-associated cryptococcal meningitis and recruited patients from six sites across five countries in Southern Africa.
I returned to the UK in 2021 and following the success of the trial I am co-investigator on a number of research and non-research grants aimed at maximising the impact of the AMBITION regimen in routine care settings and applying research advances in cryptococcal meningitis to other HIV-associated fungal infections.
Alongside research I work two-days a week for the NHS as a HIV and Sexual Health doctor.
ACADEMIC POSITIONS
- Research AssociateBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana1 Jun 2017 - present
- Honorary Associate ProfessorUniversity of the Witwatersrand, Johannesburg, South Africa1 Mar 2024 - present
NON-ACADEMIC POSITIONS
- HIV and Sexual Health DoctorKing's College Hospital NHS Foundation Trust, London, United Kingdom1 Oct 2021 - present
DEGREES
- PhDLondon School of Hygiene & Tropical Medicine, London, United Kingdom3 Jan 2023 - present
- MScDurham University, Durham, United Kingdom1 Jan 2012 - present
- MBChBUniversity of Liverpool, Liverpool, United Kingdom1 Jun 2012 - present
CERTIFICATIONS
- Diploma in HIVWorshipful Society of Apothecaries, London, United Kingdom1 Oct 2024 - present
- Diploma in Genitourinary MedicineWorshipful Society of Apothecaries, London, United Kingdom1 Aug 2022 - present
- Diploma in the Faculty of Sexual and Reproductive HealthFaculty of Sexual and Reproductive Health1 Aug 2022 - present
- Diploma in Tropical Medicine and HygieneRoyal College of Physicians, London, United Kingdom1 Jun 2018 - present
- Fellowship of the Higher Education AcademyHigher Education Academy, York, United Kingdom1 Dec 2022 - present
- MRCP(UK)Royal College of Physicians, London, United Kingdom1 Mar 2016 - present
REGIONS & COUNTRIES
- Botswana
- Malawi
- South Africa
- Sub-Saharan Africa (all income levels)
- Uganda
- United Kingdom
- Zimbabwe
- Democratic Republic of the Congo
- Guinea
- Mozambique
- Vietnam